Anti-DVL1 Polyclonal Antibody (HT161024)

Name: Anti-DVL1 Polyclonal Antibody
Brand: abinScience
SKU: HT161024
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HT161024

Description

Anti-DVL1 Polyclonal Antibody (HT161024) is a rabbit polyclonal antibody detecting DVL1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Pan troglodytes.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human DVL1 (Ser413-Leu509).

Target

DVL1, DSH homolog 1, Dishevelled-1, Segment polarity protein dishevelled homolog DVL-1

Purification

Purified by antigen affinity column.

Accession

O14640

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Segment polarity protein dishevelled homolog DVL-1 (DVL1) is a ~75 kDa protein. Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).

Note

For research use only.

Images

References

Datasheet