Anti-DVL2 Polyclonal Antibody (HT483024)

Name: Anti-DVL2 Polyclonal Antibody
Brand: abinScience
SKU: HT483024
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HT483024

Description

Anti-DVL2 Polyclonal Antibody (HT483024) is a rabbit polyclonal antibody detecting DVL2 in ELISA, IHC, WB. Suitable for Human, Mouse, Xenopus laevis, and Xenopus tropicalis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human DVL2 (Asn264-Lys353).

Target

Dishevelled-2, DVL2, DSH homolog 2, Segment polarity protein dishevelled homolog DVL-2

Purification

Purified by antigen affinity column.

Accession

O14641

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Segment polarity protein dishevelled homolog DVL-2 (DVL2) is a ~78 kDa protein. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling.

1. Geng, Y. et al. (2014) The Journal of biological chemistry 289, 11230-11241. PMID: 24616100

Note

For research use only.

Images

References

Datasheet