Anti-EFNA1 Polyclonal Antibody (HB164014)

Name: Anti-EFNA1 Polyclonal Antibody
Brand: abinScience
SKU: HB164014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HB164014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human EFNA1 (Asp19-Ser182).

Target

EPLG1, EFNA1, LERK1, Immediate early response protein B61, EPH-related receptor tyrosine kinase ligand 1, TNFAIP4, TNF alpha-induced protein 4, LERK-1, Ephrin-A1, Tumor necrosis factor alpha-induced protein 4

Purification

Purified by antigen affinity column.

Accession

P20827

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Ephrin-A1 (EFNA1) is a ~23 kDa protein. Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Involved in angiogenesis, regulating vascular endothelial cell differentiation and migration through activation of EPHA2. Acts as a ligand for EPHA3, inhibiting epithelial-to-mesenchymal transition of cardiac cells and playing a role in heart development. May also contribute to dendritic spine morphogenesis.

1. Liu, DP. et al. (2007) International journal of oncology 30, 865-71. PMID: 17332925

2. Wykosky, J. et al. (2008) Oncogene 27, 7260-73. PMID: 18794797

3. Sharfe, N. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 170, 6024-32. PMID: 12794130

Note

For research use only.

Images

References

Datasheet

Anti-EFNA1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-EFNA1 Polyclonal Antibody (HB164014)

Overview

Images

References

Datasheet

SDS

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