

| Catalog No. | VK075104 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-EHV-1 glycoprotein I/gI Polyclonal Antibody (VK075104) is a rabbit polyclonal antibody detecting envelope glycoprotein I; ORF73 in ELISA, IHC, WB.
Highlights
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| Species reactivity | Equid alphaherpesvirus 1 (EHV-1) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant ehv-1 glycoprotein I/gI (Arg26-Ser161). | ||||||||
| Target | envelope glycoprotein I; ORF73 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P68326 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Envelope glycoprotein I (gI) is a ~46 kDa protein. In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system. Together with US9, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips. | ||||||||
| Note | For research use only |
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