

| Catalog No. | HW802014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human ETFB (Ala2-Ile255). | ||||||||
| Target | Beta-ETF, ETFB, Electron transfer flavoprotein subunit beta | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P38117 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| Product Usage Information |
| ||||||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Electron transfer flavoprotein subunit beta (ETFB) is a ~27 kDa protein. Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (Probable). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. ETFB binds an AMP molecule that probably has a purely structural role. 1. Toogood, HS. et al. (2004) The Journal of biological chemistry 279, 32904-12. PMID: 15159392 2. Toogood, HS. et al. (2005) The Journal of biological chemistry 280, 30361-6. PMID: 15975918 3. Małecki, J. et al. (2015) The Journal of biological chemistry 290, 423-34. PMID: 25416781 4. Olsen, RK. et al. (2003) Human mutation 22, 12-23. PMID: 12815589 5. Colombo, I. et al. (1994) Human molecular genetics 3, 429-35. PMID: 7912128 6. Roberts, DL. et al. (1996) Proceedings of the National Academy of Sciences of the United States of America 93, 14355-60. PMID: 8962055 | ||||||||
| Note | For research use only. |
Contact us for custom quotes, bulk requests and any other issues.
Mail: [email protected]
+86-27-65523339
Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский