

| Catalog No. | HX170014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-FKBP4 Polyclonal Antibody (HX170014) is a rabbit polyclonal antibody detecting FKBP4 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human FKBP4 (Thr2-Ala459). | ||||||||
| Target | PPIase FKBP4, FKBP51, HSP-binding immunophilin, FKBP52, p59, HBI, Rotamase, Peptidyl-prolyl cis-trans isomerase FKBP4, FKBP4, FKBP59, 51 kDa FK506-binding protein, 52 kDa FK506-binding protein, FK506-binding protein 4, FKBP-4, 59 kDa immunophilin, FKBP-52, Immunophilin FKBP52, 52 kDa FKBP | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q02790 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Peptidyl-prolyl cis-trans isomerase FKBP4 is a ~51 kDa protein. Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Also acts as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. | ||||||||
| Note | For research use only. |
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