

| Catalog No. | HW410014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-FNTA Polyclonal Antibody (HW410014) is a rabbit polyclonal antibody detecting FNTA in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human FNTA (Met51-Lys366). | ||||||||
| Target | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, FTase-alpha, FNTA, GGTase-I-alpha, CAAX farnesyltransferase subunit alpha, Ras proteins prenyltransferase subunit alpha | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P49354 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) is a ~44 kDa protein. Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. | ||||||||
| Note | For research use only. |
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