

| Catalog No. | VK804014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-FPV Capsid protein VP1/VP2 Polyclonal Antibody (VK804014) is a rabbit polyclonal antibody detecting Capsid protein VP1 in ELISA, IHC, WB.
Highlights
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| Species reactivity | Feline panleukopenia virus (FPV) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant FPV Capsid protein VP1 (Val181-Asp321). | ||||||||
| Target | Capsid protein VP1, Coat protein VP1 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P04864 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Capsid protein VP1 is a ~80 kDa protein. Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptor TFRC. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-FPV-VP1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant FPV Capsid protein VP1/VP2 (Catalog No: VK804012)
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