

| Catalog No. | HY170014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human FTH1 (Thr2-Ser183). | ||||||||
| Target | FTH, FTH1, FTHL6, Ferritin H subunit, Cell proliferation-inducing gene 15 protein, Ferritin heavy chain | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P02794 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Ferritin heavy chain (FTH1) is a ~21 kDa protein. Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. 1. Treffry, A. et al. (1997) Biochemistry 36, 432-41. PMID: 9003196 2. Mancias, JD. et al. (2014) Nature 509, 105-9. PMID: 24695223 3. Mancias, JD. et al. (2015) eLife 4. PMID: 26436293 | ||||||||
| Note | For research use only. |
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