Anti-GAA Polyclonal Antibody (HY377014)

Name: Anti-GAA Polyclonal Antibody
Brand: abinScience
SKU: HY377014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HY377014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human GAA (Pro595-Gly770).

Target

GAA, Lysosomal alpha-glucosidase, Acid maltase, Aglucosidase alfa

Purification

Purified by antigen affinity column.

Accession

P10253

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Lysosomal alpha-glucosidase (GAA/Aglucosidase alfa) is a ~105 kDa protein. Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans.

1. Hermans, MM. et al. (2004) Human mutation 23, 47-56. PMID: 14695532

2. Pittis, MG. et al. (2008) Human mutation 29, E27-36. PMID: 18429042

3. Hermans, MM. et al. (1991) The Journal of biological chemistry 266, 13507-12. PMID: 1856189

4. Boerkoel, CF. et al. (1995) American journal of human genetics 56, 887-97. PMID: 7717400

5. Roig-Zamboni, V. et al. (2017) Nature communications 8, 1111. PMID: 29061980

Note

For research use only.

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