Anti-galactose-deficient IgA1 Recombinant Antibody (KM55) (HV621013)

Name: Anti-galactose-deficient IgA1 Recombinant Antibody (KM55)
Brand: abinScience
SKU: HV621013
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HV621013
Species reactivity	Human
Applications	ELISA, IF, IHC
Host species	Rat
Isotype	IgG2b, kappa
Clone ID	KM55
Clonality	Monoclonal
Target	galactose-deficient IgA1, Gd-IgA1, IGHA1, Ig alpha-1 chain C region, Ig alpha-1 chain C region BUR, Ig alpha-1 chain C region TRO, Immunoglobulin heavy constant alpha 1
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P01876
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Immunoglobulin heavy constant alpha 1 (Gd-IgA1) is a ~42 kDa protein. Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. 1. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268 2. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414 3. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170 4. Kerr, MA. (1990) The Biochemical journal 271, 285-96. PMID: 2241915
Note	For research use only

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Datasheet

Anti-galactose-deficient IgA1 Recombinant Antibody (KM55).pdf

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Anti-galactose-deficient IgA1 Recombinant Antibody (KM55) (HV621013)

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