Anti-Ganglioside GD3 Recombinant Antibody (R24) (YP464023)

Name: Anti-Ganglioside GD3 Recombinant Antibody (R24)
Brand: abinScience
SKU: YP464023
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

YP464023

Description

Anti-Ganglioside GD3 Recombinant Antibody (R24) (YP464023) is a human monoclonal antibody detecting Ganglioside GD3 in ELISA. Suitable for General.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

Species reactivity

General

Applications

ELISA

Host species

Human

Clonality

Monoclonal

Isotype

IgG1

Clone ID

R24

Target

Disialoganglioside GD3, GD3 ganglioside, α-N-acetylneuraminosyl-(2→8)-α-N-acetylneuraminosyl-(2→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1')-ceramide

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

ChEBI: 28424, PubChem CID: 20057323

RRID

Anti-Ganglioside GD3 Antibody (R24) (abinScience Cat# YP464023, RRID:AB_3727080)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Mitumomab is an anti-idiotypic mouse IgG2b monoclonal antibody that mimics the ganglioside GD3. Mitumomab can be used for the research of small-cell lung carcinoma.
• GD3 ganglioside and apoptosis., PMID:12531552
• Ganglioside GD3: structure, cellular distribution, and possible function., PMID:3903474
• Ganglioside GD3 as a raft component in cell death regulation., PMID:21554197
• A reappraisal of ganglioside GD3 expression in the CNS., PMID:8721669
• Ganglioside GD3 regulates neural stem cell quiescence and controls postnatal neurogenesis., PMID:37667994
• Ganglioside GD3 is up-regulated in microglia and regulates phagocytosis following global cerebral ischemia., PMID:34133773
• Ganglioside GD3 regulates dendritic growth in newborn neurons in adult mouse hippocampus via modulation of mitochondrial dynamics., PMID:32743804
• Possible regulation of ganglioside GD3 synthase gene expression with DNA methylation in human glioma cells., PMID:36897478
• Ganglioside GD3 Regulates Inflammation and Epithelial-to-Mesenchymal Transition in Human Nasal Epithelial Cells., PMID:38612859
• Development of Fluorescent Ganglioside GD3 and GQ1b Analogs for Elucidation of Raft-Associated Interactions., PMID:32951428

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Ganglioside GD3 Antibody (R24)

References

Datasheet

Anti-Ganglioside GD3 Recombinant Antibody (R24).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Ganglioside GD3 Recombinant Antibody (R24) (YP464023)

Overview

Images

References

Datasheet

SDS