Anti-GDNF Polyclonal Antibody (HW706014)

Name: Anti-GDNF Polyclonal Antibody
Brand: abinScience
SKU: HW706014
Price: 168 USD
Availability: InStock

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Overview

Catalog No.

HW706014

Description

Anti-GDNF Polyclonal Antibody (HW706014) is a rabbit polyclonal antibody detecting GDNF in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human GDNF (Ser78-Gly107).

Target

hGDNF, Astrocyte-derived trophic factor, Glial cell line-derived neurotrophic factor, ATF, GDNF

Purification

Purified by antigen affinity column.

Accession

P39905

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Glial cell line-derived neurotrophic factor (GDNF) is a ~23 kDa protein. Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. Acts by binding to its coreceptor, GFRA1, leading to autophosphorylation and activation of the RET receptor. Involved in the development of the neural crest.

1. Lin, LF. et al. (1993) Science (New York, N.Y.) 260, 1130-2. PMID: 8493557

2. Cik, M. et al. (2000) The Journal of biological chemistry 275, 27505-12. PMID: 10829012

3. Goodman, KM. et al. (2014) Cell reports 8, 1894-1904. PMID: 25242331

4. Li, J. et al. (2019) eLife 8. PMID: 31535977

5. Yan, H. et al. (2004) Developmental biology 272, 118-33. PMID: 15242795

Note

For research use only.

Images

References

Datasheet

Anti-GDNF Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-GDNF Polyclonal Antibody (HW706014)

Overview

Images

References

Datasheet

SDS

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