Anti-GPI Polyclonal Antibody (HY491014)

Name: Anti-GPI Polyclonal Antibody
Brand: abinScience
SKU: HY491014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HY491014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human GPI (Met263-Asn475).

Target

GPI, NLK, Neuroleukin, Phosphohexose isomerase, PHI, Sperm antigen 36, Autocrine motility factor, AMF, SA-36, PGI, Glucose-6-phosphate isomerase, Phosphoglucose isomerase

Purification

Purified by antigen affinity column.

Accession

P06744

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Glucose-6-phosphate isomerase (GPI) is a ~63 kDa protein. Isomerase that catalyzes the conversion of alpha-D-glucose-6-phosphate to beta-D-fructose-6-phosphate, the second step in glycolysis, and the reverse reaction in gluconeogenesis, within the cytoplasm. Also shows C2-epimerase activity, interconverting D-glucose-6-phosphate (G6P) and D-mannose-6-phosphate (M6P). Also displays anomerase activity, interconverting alpha and beta-anomeric forms of G6P, D-fructose-6-phosphate and M6P. In addition to its metabolic role, this enzyme functions extracellularly as a cytokine: acts as autocrine motility factor (AMF), a secreted angiogenic factor that enhances endothelial cell motility. Functions as neuroleukin, a neurotrophic factor supporting the survival of spinal and sensory neurons.

1. Mojzikova, R. et al. (2018) Blood cells, molecules & diseases 69, 23-29. PMID: 28803808

2. Funasaka, T. et al. (2001) Biochemical and biophysical research communications 285, 118-28. PMID: 11437381

3. Haga, A. et al. (2000) Biochimica et biophysica acta 1480, 235-44. PMID: 11004567

4. Faik, P. et al. (1988) Nature 332, 455-7. PMID: 3352745

Note

For research use only.

Images

References

Datasheet

Anti-GPI Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Anti-GPI Polyclonal Antibody (HY491014)

Overview

Images

References

Datasheet

SDS

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