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Anti-GPR137B Polyclonal Antibody (HB590014)

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Overview
Catalog No.HB590014
Description
Anti-GPR137B Polyclonal Antibody (HB590014) is a rabbit polyclonal antibody detecting Integral membrane protein GPR137B; Transmembrane 7 superfamily member 1 protein; GPR137B; TM7SF1 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant human GPR137B (Val315-Gly399).
Target Integral membrane protein GPR137B; Transmembrane 7 superfamily member 1 protein; GPR137B; TM7SF1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession O60478, Q8BNQ3
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Integral membrane protein GPR137B is a ~45 kDa protein. Lysosomal integral membrane protein that regulates the localization and activity of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Interacts with Rag GTPases and increases the lysosomial localization and activity of Rag GTPases and thereby regulates mTORC1 translocation and activity in lysosome. Involved in the regulation of lysosomal morphology and autophagy.

1. Gan, L. et al. (2019) Nature cell biology 21, 614-626. PMID: 31036939
Note For research use only
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Formula
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Anti-GPR137B Polyclonal Antibody

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