

| Catalog No. | HC633014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-GRB7 Polyclonal Antibody (HC633014) is a rabbit polyclonal antibody detecting GRB7 in ELISA, IHC, WB. Suitable for Bovine, Human, Mouse, and Rat.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human GRB7 (Ser66-Thr327). | ||||||||
| Target | GRB7, Growth factor receptor-bound protein 7, GRB7 adapter protein, Epidermal growth factor receptor GRB-7, B47 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q14451 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Growth factor receptor-bound protein 7 (GRB7) is a ~59 kDa protein. Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. | ||||||||
| Note | For research use only. |
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