

| Catalog No. | HV354014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human GRIP1 (Gly874-Glu1073). | ||||||||
| Target | GRIP-1, Glutamate receptor-interacting protein 1, GRIP1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9Y3R0 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Glutamate receptor-interacting protein 1 (GRIP1) is a ~122 kDa protein. May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons. Through complex formation with NSG1, GRIA2 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting. 1. Brückner, K. et al. (1999) Neuron 22, 511-24. PMID: 10197531 | ||||||||
| Note | For research use only. |
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