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Anti-GRK3 Polyclonal Antibody (HB509014)

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Overview
Catalog No.HB509014
Description
Anti-GRK3 Polyclonal Antibody (HB509014) is a rabbit polyclonal antibody detecting G protein-coupled receptor kinase 3; 2.7.11.15; Beta-adrenergic receptor kinase 2; Beta-ARK-2; GRK3; ADRBK2; BARK2 in ELISA, IHC, WB. Suitable for Human, Bovine, Mouse, and Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant human GRK3 (Met188-Gly475).
Target G protein-coupled receptor kinase 3; 2.7.11.15; Beta-adrenergic receptor kinase 2; Beta-ARK-2; GRK3; ADRBK2; BARK2
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P35626, P26818, Q3UYH7, P26819, P21146, P25098, Q99MK8, P26817
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

G protein-coupled receptor kinase 3 (GRK3) is a ~79 kDa protein. receptors. Also phosphorylates ligand-bound C3a and C5a anaphylatoxin receptors (C3AR1 and C5AR1, respectively), leading to receptor desensitization.

1. Guo, Q. et al. (2011) PloS one 6, e22559. PMID: 21799898
Note For research use only
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Datasheet
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Formula
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C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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C₂ (Working Conc.)
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Anti-GRK3 Polyclonal Antibody

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