

| Catalog No. | HX884014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-GSTM4 Polyclonal Antibody (HX884014) is a rabbit polyclonal antibody detecting GSTM4 in ELISA, IHC, WB. Suitable for Mouse, Human, Macaca fascicularis, and Rat.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human GSTM4 (Arg18-Trp215). | ||||||||
| Target | GSTM4-4, Glutathione S-transferase Mu 4, GSTM4, GST-Mu2, Leukotriene C4 synthase GSTM4, GST class-mu 4 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q03013 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Glutathione S-transferase Mu 4 (GSTM4) is a ~25 kDa protein. Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4. Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions. 1. Comstock, KE. et al. (1994) Archives of biochemistry and biophysics 311, 487-95. PMID: 8203914 2. Ross, VL. et al. (1993) The Biochemical journal 294 ( Pt 2), 373-80. PMID: 8373352 3. Dalli, J. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 12232-12237. PMID: 27791009 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-GSTM4 polyclonal antibody at 1ug/mL on recombinant GSTM4 (Catalog No. HX884012).
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