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Anti-H2AC4 Polyclonal Antibody (HY314014)

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Overview
Catalog No.HY314014
Description
Anti-H2AC4 Polyclonal Antibody (HY314014) is a rabbit polyclonal antibody detecting H2AC4 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Acropora formosa, and Aspergillus niger.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human H2AC4 (Met1-Lys130).
Target HIST1H2AB, Histone H2A.2, Histone H2A type 1-B/E, Histone H2A/m, HIST1H2AE, H2AFA, Histone H2A/a, H2AC4, H2AFM
Purification Purified by antigen affinity column.
Accession P04908
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Histone H2A type 1-B/E (H2AC4) is a ~14 kDa protein. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Note For research use only.
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Formula
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Anti-H2AC4 Polyclonal Antibody

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