

| Catalog No. | VK550034 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-HAdV-3 Protease/L3 Polyclonal Antibody (VK550034) is a rabbit polyclonal antibody detecting Protease in ELISA, WB.
Highlights
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| Species reactivity | Human adenovirus B serotype 3 (HAdV-3) | ||||||||
| Applications | ELISA, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant HAdV-3 Protease/L3 (Met1-Gln209). | ||||||||
| Target | Protease, 3.4.22.39, Adenain, Adenovirus protease, AVP, Adenovirus proteinase, Endoprotease, L3 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P10381 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Protease (L3) is a ~23 kDa protein. Cleaves viral precursor proteins (pTP, pIIIa, pVI, pVII, pVIII, and pX) inside newly assembled particles giving rise to mature virions. Protease complexed to its cofactor slides along the viral DNA to specifically locate and cleave the viral precursors. Mature virions have a weakened organization compared to the unmature virions, thereby facilitating subsequent uncoating. Without maturation, the particle lacks infectivity and is unable to uncoat. Late in adenovirus infection, in the cytoplasm, may participate in the cytoskeleton destruction. | ||||||||
| Note | For research use only. |
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