Anti-HAdV-5 Fiber protein/L5 Polyclonal Antibody (VK764014)

Name: Anti-HAdV-5 Fiber protein/L5 Polyclonal Antibody
Brand: abinScience
SKU: VK764014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

VK764014

Description

Anti-HAdV-5 Fiber protein/L5 Polyclonal Antibody (VK764014) is a rabbit polyclonal antibody detecting Fiber protein in ELISA, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

Species reactivity

Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)

Applications

ELISA, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant HAdV-5 Fiber protein/L5 (Gly387-Glu581).

Target

Fiber protein, SPIKE, Protein IV, L5

Purification

Purified by antigen affinity column.

Accession

P11818

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Fiber protein (L5) is a ~61 kDa protein. Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host coxsackievirus and adenovirus receptor CXADR located at the cell tight junctions to provide virion initial attachment to target cell. The fiber protein binds to CXADR with a higher affinity than CXADR binds to itself, thereby blocking the cell-cell adhesion function of CXADR dimers and leading to local disruption of the tight junction. Fiber protein present on neo-synthesized particles may thus disrupt the junctional integrity in order to facilitate further neighboring cells infection. Fiber proteins are shed during virus entry, when virus is still at the cell surface.

Note

For research use only.

Images

References

Datasheet

Anti-HAdV-5 Fiber protein/L5 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-HAdV-5 Fiber protein/L5 Polyclonal Antibody (VK764014)

Overview

Images

References

Datasheet

SDS

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