

| Catalog No. | HY584014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human HARS1 (Met1-Gln294). | ||||||||
| Target | HRS, HARS, HisRS, Histidyl-tRNA synthetase, HARS1, Histidine--tRNA ligase, cytoplasmic | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P12081 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Histidine--tRNA ligase, cytoplasmic (HARS1) is a ~57 kDa protein. Catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP). Plays a role in axon guidance. 1. Abbott, JA. et al. (2018) Human mutation 39, 415-432. PMID: 29235198 2. Safka Brozkova, D. et al. (2015) Brain : a journal of neurology 138, 2161-72. PMID: 26072516 | ||||||||
| Note | For research use only. |




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