

| Catalog No. | VK690014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Hepatitis B virus (HBV) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant HBV X/HBx (Ala2-Ala154). | ||||||||
| Target | Protein X, HBx, Peptide X, pX, X | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P03165 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Protein X (HBx) is a ~16 kDa protein. Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription. Does not seem to be essential for HBV infection. May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma). Most of cytosolic activities involve modulation of cytosolic calcium. The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted. | ||||||||
| Note | For research use only. |
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