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Anti-HCV NS5A Polyclonal Antibody (VK600014)

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Overview
Catalog No.VK600014
Description
Anti-HCV NS5A Polyclonal Antibody (VK600014) is a rabbit polyclonal antibody detecting NS5A. Suitable for Hepatitis C virus genotype 1b.
Species reactivityHepatitis C Virus (HCV)
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant HCV NS5A (Ser2010-Val2170).
Target Capsid protein C, Core protein precursor, EC:2.7.7.48, EC:3.4.21.98, EC:3.4.22.-, EC:3.6.1.15, EC:3.6.4.13, Envelope glycoprotein E1, Envelope glycoprotein E2, Genome polyprotein, Hepacivirin, Mature core protein, NS1, NS3 helicase, NS3 protease, NS3P, NS4A, NS4B, NS5A, NS5B, Non-structural protein 4A, Non-structural protein 4B, Non-structural protein 5A, Protease NS2, RNA-directed RNA polymerase, Serine protease/helicase NS3, Viroporin p7, Viroporin p70, gp32, gp35, gp68, gp70, p21, p23, p27, p56/58, p68, p8
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q9WMX2
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Genome polyprotein (NS5A) is a ~326 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication. Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable).

Note For research use only
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Formula
C₁ × V₁ = C₂ × V₂
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