Please ensure Javascript is enabled for purposes of website accessibility
Home > Products > Antibodies > Primary antibodies

Anti-Hepatitis E virus/HEV ORF3 Antibody (SAA2695) (VK620073)

Price(USD): $
Spec:
  • 50ug
  • 100ug
  • 1mg
Number:
Contact us
  • Overview

  • Images

  • References

  • Datasheet

Overview
Catalog No.VK620073
Description
Anti-Hepatitis E virus/HEV ORF3 Antibody (SAA2695) [SAA2695] (VK620073) is a human monoclonal antibody detecting Protein ORF3 in ELISA, IF, WB.
Highlights
  • Multi-Application — Validated across multiple applications.
Species reactivityHepatitis E virus (HEV)
ApplicationsELISA, IF, WB
Host speciesHuman
IsotypeIgG1
Clone IDSAA2695
Clonality Monoclonal
Target Protein ORF3
Endotoxin level <10 EU/mg
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession E9N3C1
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Protein ORF3 is a ~11 kDa protein. Small multifunctional phosphoprotein involved in virion morphogenesis, egress and counteracting host innate immunity. Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. Also acts as a viroporin and forms ion conductive pores allowing viral particle release. Impairs the generation of type I interferon by down-regulating host TLR3 and TLR7 as well as their downstream signaling pathways. Down-regulates the phosphorylation of host IRF3 via the interaction with host SIRP-alpha, thereby inhibiting IFN-I expression.

Note For research use only
Images
References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommendation

Contact us for custom quotes, bulk requests and any other issues.

Mail: support@abinScience.com

Distributor list