Anti-HIF2A/EPAS1 Polyclonal Antibody (HV758014)

Name: Anti-HIF2A/EPAS1 Polyclonal Antibody
Brand: abinScience
SKU: HV758014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

HV758014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human HIF2A/EPAS1 (Leu239-Asn350).

Target

Basic-helix-loop-helix-PAS protein MOP2, bHLHe73, HIF-2-alpha, Member of PAS protein 2, PAS domain-containing protein 2, HIF2A, HLF, EPAS1, Endothelial PAS domain-containing protein 1, EPAS-1, HIF-1-alpha-like factor, Hypoxia-inducible factor 2-alpha, MOP2, HIF2-alpha, BHLHE73, PASD2, Class E basic helix-loop-helix protein 73

Purification

Purified by antigen affinity column.

Accession

Q99814

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Endothelial PAS domain-containing protein 1 (HIF2A/EPAS1) is a ~96 kDa protein. Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression.

Note

For research use only.

Images

References

Datasheet

Anti-HIF2A/EPAS1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Anti-HIF2A/EPAS1 Polyclonal Antibody (HV758014)

Overview

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References

Datasheet

SDS

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