

| Catalog No. | HM832383 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA, SPR | ||||
| Host species | Human | ||||
| Clonality | Monoclonal | ||||
| Isotype | IgG, kappa | ||||
| Clone ID | REGN6972 | ||||
| Target | HLA class I histocompatibility antigen, A alpha chain, HLA-A, HLAA, Human leukocyte antigen A, CT1.4, Cancer/testis antigen 1.4, MAGE-4 antigen, MAGE-41 antigen, MAGE-X2 antigen, MAGE4, MAGEA4, Melanoma-associated antigen 4 | ||||
| Endotoxin level | < 10 EU/mg | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P04439 & P43358 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
| ||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Melanoma-associated antigen 4 (HLA-A2-peptide (FMNKFIYEI) Complex) is a ~34 kDa protein. Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase. Also negatively regulates p53-mediated apoptosis. 1. Bhan, S. et al. (2012) Oncology reports 28, 1498-502. PMID: 22842486 | ||||
| Note | For research use only | ||||
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |

SDS-PAGE for Anti-HLA-A2-peptide (GVYDGREHTV) Complex (REGN6972)
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