Please ensure Javascript is enabled for purposes of website accessibility
Contact us Contact Us
EN
Home > Products > Antibodies > Primary antibodies

Anti-HMGB2 Polyclonal Antibody (HB755014)

Datasheet Share product Copy info
Price(USD):
Spec:
  • 50ug
  • 100ug
Number:
Get quote

  • Overview

  • Images

  • References

  • Datasheet

  • SDS

Overview
Catalog No.HB755014
Description
Anti-HMGB2 Polyclonal Antibody (HB755014) is a rabbit polyclonal antibody detecting HMGB2 in ELISA, IHC, WB. Suitable for Mouse, Bovine, Callithrix jacchus, Dog, and Equus caballus.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human HMGB2 (Gly2-Pro187).
Target HMGB2, High mobility group protein 2, HMG-2, HMG2, High mobility group protein B2
Purification Purified by antigen affinity column.
Accession P26583
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

High mobility group protein B2 (HMGB2) is a ~24 kDa protein. Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. In the nucleus is an abundant chromatin-associated non-histone protein involved in transcription, chromatin remodeling and V(D)J recombination and probably other processes. Binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor binding and/or bringing distant regulatory sequences into close proximity.

1. Fan, Z. et al. (2002) Molecular and cellular biology 22, 2810-20. PMID: 11909973
2. Zimmerman, J. et al. (2008) Biochemical and biophysical research communications 371, 79-84. PMID: 18413230
3. Ugrinova, I. et al. (2009) Biochemistry 48, 6502-7. PMID: 19522541
4. Laurent, B. et al. (2010) Blood 115, 687-95. PMID: 19965638
5. Stros, M. (2010) Biochimica et biophysica acta 1799, 101-13. PMID: 20123072
6. Shykind, BM. et al. (1995) Genes & development 9, 1354-65. PMID: 7797075
7. Pusterla, T. et al. (2009) Autoimmunity 42, 308-10. PMID: 19811285
8. Küchler, R. et al. (2013) Antimicrobial agents and chemotherapy 57, 4782-93. PMID: 23877675
Note For research use only.
Images
References
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommendation

Contact us for custom quotes, bulk requests and any other issues.

Mail: [email protected]

Distributor list

Get a free quote
Anti-HMGB2 Polyclonal Antibody

Quick access

Contact Us

  • +86-27-65523339

  • [email protected]

  • Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China

  • linkedin
  • Ins
  • youtube
  • youtube
Copyright © 2026 abinScience. All Rights Reserved. All Products are for Research Use Only