

| Catalog No. | HW638014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human HNF1B (Pro159-Phe300). | ||||||||
| Target | TCF-2, HNF-1-beta, TCF2, HNF1B, Variant hepatic nuclear factor 1, Homeoprotein LFB3, vHNF1, Hepatocyte nuclear factor 1-beta, HNF-1B, Transcription factor 2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P35680 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Hepatocyte nuclear factor 1-beta (HNF1B) is a ~61 kDa protein. Transcription factor that binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Binds to the FPC element in the cAMP regulatory unit of the PLAU gene. Transcriptional activity is increased by coactivator PCBD1. 1. Lu, P. et al. (2007) Biochemistry 46, 12071-80. PMID: 17924661 2. Bach, I. et al. (1993) The EMBO journal 12, 4229-42. PMID: 7900999 3. Ferrè, S. et al. (2014) Journal of the American Society of Nephrology : JASN 25, 574-86. PMID: 24204001 | ||||||||
| Note | For research use only. |




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