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Anti-HPGDS Polyclonal Antibody (HT490014)

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Overview
Catalog No.HT490014
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human HPGDS (Met1-Leu199).
Target GST class-sigma, Prostaglandin-H2 D-isomerase, PTGDS2, Glutathione-dependent PGD synthase, Hematopoietic prostaglandin D synthase, PGDS, HPGDS, Glutathione-requiring prostaglandin D synthase, GSTS, H-PGDS, Glutathione S-transferase
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession O60760
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Hematopoietic prostaglandin D synthase (HPGDS) is a ~23 kDa protein. Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.

References 1. Niitsu Y, et al. Implications of glutathione-S transferase P1 in MAPK signaling as a CRAF chaperone: In memory of Dr. Irving Listowsky. Proc Jpn Acad Ser B Phys Biol Sci. 2022;98(2):72-86. [HT490014]
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-HPGDS Polyclonal Antibody

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