

| Catalog No. | VK639014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human papillomavirus type 18 | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant HPV18 L1/Major capsid protein L1 (Val82-Gly535). | ||||||||
| Target | Major capsid protein L1, L1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P06794 | ||||||||
| RRID | Anti-HPV18 L1/Major capsid protein L1 Polyclonal Antibody (abinScience Cat# VK639014, RRID:AB_3723062) |
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| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Major capsid protein L1 is a ~63 kDa protein. Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-HPV18 L1/Major capsid protein L1 polyclonal antibody at 1ug/mL on recombinant HPV18 L1/Major capsid protein L1 (Catalog No. VK639012).




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