Anti-HPV52 E6/Protein E6 Polyclonal Antibody (VK412014)

Name: Anti-HPV52 E6/Protein E6 Polyclonal Antibody
Brand: abinScience
SKU: VK412014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

VK412014

Description

Anti-HPV52 E6/Protein E6 Polyclonal Antibody (VK412014) is a rabbit polyclonal antibody detecting Protein E6 in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human papillomavirus 52 (HPV52)

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant HPV52 E6/Protein E6 (Met1-Val148).

Target

Protein E6, E6

Purification

Purified by antigen affinity column.

Accession

P36814

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Protein E6 is a ~17 kDa protein. Plays a major role in the induction and maintenance of cellular transformation. Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase, and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation. In turn, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development. The complex E6/E6AP targets several other substrates to degradation via the proteasome including host DLG1 or NFX1, a repressor of human telomerase reverse transcriptase (hTERT).

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-HPV52 E6/Protein E6 polyclonal antibody at 1ug/mL on recombinant HPV52 E6/Protein E6 (Catalog No. VK412012).

References

Datasheet

Anti-HPV52 E6/Protein E6 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-HPV52 E6/Protein E6 Polyclonal Antibody (VK412014)

Overview

Images

References

Datasheet

SDS

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