

| Catalog No. | HV597014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-HS2ST1 Polyclonal Antibody (HV597014) is a rabbit polyclonal antibody detecting HS2ST1 in ELISA, IHC, WB. Suitable for Human, Mouse, Cricetulus griseus, Chicken, and Pongo abelii.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human HS2ST1 (Asn29-Trp229). | ||||||||
| Target | HS2ST1, HS2ST, 2OST, Heparan sulfate 2-O-sulfotransferase 1, KIAA0448, 2-O-sulfotransferase | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q7LGA3 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) is a ~41 kDa protein. Catalyzes the transfer of a sulfo group from 3'-phospho-5'-adenylyl sulfate (PAPS) to the 2-OH position of iduronic acid (IdoA) or glucuronic acid (GlcA) within the heparan sulfate (HS) chain and participates in HS biosynthesis. Required for metanephric development of kidney formation, suggesting that 2-O-sulfation within HS is essential for signaling between ureteric bud and metanephric mesenchyme. | ||||||||
| Note | For research use only. |
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