Anti-HSV-1/HHV-1 gE Polyclonal Antibody (VK746014)

Name: Anti-HSV-1/HHV-1 gE Polyclonal Antibody
Brand: abinScience
SKU: VK746014
Price: 168 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

VK746014

Description

Anti-HSV-1/HHV-1 gE Polyclonal Antibody (VK746014) is a rabbit polyclonal antibody detecting HSV-1/HHV-1 gE in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant HSV-1/HHV-1 gE (Lys24-Arg419).

Target

gE, Envelope glycoprotein E

Purification

Purified by antigen affinity column.

Accession

P04488

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Envelope glycoprotein E (gE) is a ~59 kDa protein. In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system. Together with US9, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips.

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-HSV-1/HHV-1 gE polyclonal antibody at 1ug/mL on recombinant HSV-1/HHV-1 gE (Catalog No. VK746012).

References

Datasheet