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Anti-HSV Glycoprotein B/gB Recombinant Antibody (SAA2517) (VK006063)

Anti-HSV Glycoprotein B/gB Recombinant Antibody (SAA2517)
Anti-HSV Glycoprotein B/gB Recombinant Antibody (SAA2517)
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  • 100ug
  • 1mg
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Overview
Catalog No.VK006063
Description
Anti-HSV Glycoprotein B/gB Antibody (SAA2517) [SAA2517] (VK006063) is a mouse monoclonal antibody detecting HSV Glycoprotein B/gB in ELISA, Neutralization, FCM.
Highlights
  • Multi-Application — Validated across multiple applications.
  • Flow Cytometry — Validated for flow cytometry applications.
Species reactivityHuman herpesvirus 1 (HHV-1) (Human herpes simplex virus 1), Human herpesvirus 2 (HHV-2) (Human herpes simplex virus 2)
ApplicationsELISA, Neutralization, FCM
Host speciesMouse
IsotypeIgG
Clone IDSAA2517
Clonality Monoclonal
Target gB
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P06437, P08666
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Envelope glycoprotein B (gB) is a ~100 kDa protein. Envelope glycoprotein that forms spikes at the surface of virion envelope and binds to the host cell entry receptors MYH9/NMMHC-IIA and MYH10/NMMHC-IIB, promoting the virus entry into host cells. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell: following initial binding to its host cell entry receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress. Also plays a role, together with gK, in virus-induced cell-to-cell fusion (syncytia formation).

Note For research use only
Images
  • Anti-HSV Glycoprotein B/gB Recombinant Antibody (SAA2517)

    SDS-PAGE

    SDS-PAGE for Anti-HSV Glycoprotein B/gB Antibody (SAA2517)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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