Anti-Human a1AT/Serpin A1/SERPINA1 Polyclonal Antibody (HF638014)

Name: Anti-Human a1AT/Serpin A1/SERPINA1 Polyclonal Antibody
Brand: abinScience
SKU: HF638014
Price: 96 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HF638014

Description

Anti-Human a1AT/Serpin A1/SERPINA1 Polyclonal Antibody (HF638014) is a rabbit polyclonal antibody detecting Serpin A1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human a1AT/Serpin A1/SERPINA1 (Thr46-Lys418).

Target

Alpha-1-antitrypsin, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, Short peptide from AAT, SPAAT, SERPINA1, AAT, PI

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

P01009

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Alpha-1-antitrypsin (SERPINA1) is a ~46 kDa protein. Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.

Note

For research use only

Images

Western blot

Western blot analysis was performed using anti-SERPINA1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse kidney lysate
Lane 2: Rat lung lysate
Lane 3: Rat kidney lysate