

| Catalog No. | HT028013 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Mouse | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | SAA1752 | ||||
| Clonality | Monoclonal | ||||
| Target | Non-muscle alpha-actinin 4, Alpha-actinin-4, ACTN4 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | O43707 | ||||
| RRID | Anti-Human ACTN4/Actinin alpha 4 Antibody (SAA1752) (abinScience Cat# HT028013, RRID:AB_3727513) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Alpha-actinin-4 (ACTN4) is a ~104 kDa protein. F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. 1. Yan, Q. et al. (2005) Molecular biology of the cell 16, 2470-82. PMID: 15772161 2. Khurana, S. et al. (2012) The Journal of biological chemistry 287, 12027-35. PMID: 22351778 3. Gordón-Alonso, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 689-700. PMID: 22689882 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human ACTN4/Actinin alpha 4 Antibody (SAA1752)
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