Anti-Human ADGRG2/GPR64 Recombinant Antibody (SAA1866) (HA124013)

Name: Anti-Human ADGRG2/GPR64 Recombinant Antibody (SAA1866)
Brand: abinScience
SKU: HA124013
Price: 196 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HA124013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1866

Clonality

Monoclonal

Target

Adhesion G-protein coupled receptor G2, HE6, TM7LN2, Human epididymis-specific protein 6, ADGRG2, He6, G-protein coupled receptor 64, GPR64

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8IZP9

RRID

Anti-Human ADGRG2/GPR64 Antibody (SAA1866) (abinScience Cat# HA124013, RRID:AB_3727629)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Adhesion G-protein coupled receptor G2 (ADGRG2/GPR64) is a ~111 kDa protein. Adhesion G-protein coupled receptor (aGPCR) for steroid hormones, such as dehydroepiandrosterone (DHEA; also named 3beta-hydroxyandrost-5-en-17-one) and androstenedione. Involved in a signal transduction pathway controlling epididymal function and male fertility. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG2 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. Also able to couple with G(q) G proteins in vitro.

1. Zhang, DL. et al. (2018) eLife 7. PMID: 29393851

2. Lin, H. et al. (2022) Nature chemical biology 18, 1196-1203. PMID: 35982227

3. Yang, Z. et al. (2025) Cell 188, 1589-1604.e24. PMID: 39884271

4. Sun, Y. et al. (2021) The Journal of biological chemistry 296, 100174. PMID: 33303626

5. Gad, AA. et al. (2021) Scientific reports 11, 14060. PMID: 34234254

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human ADGRG2/GPR64 Antibody (SAA1866)

References

Datasheet

Anti-Human ADGRG2/GPR64 Recombinant Antibody (SAA1866).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human ADGRG2/GPR64 Recombinant Antibody (SAA1866) (HA124013)

Overview

Images

References

Datasheet

SDS

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