

| Catalog No. | HF992014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human ADGRL1 Polyclonal Antibody (HF992014) is a rabbit polyclonal antibody detecting ADGRL1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human ADGRL1 (Gly142-Gly397). | ||||||||
| Target | Adhesion G protein-coupled receptor L1, Calcium-independent alpha-latrotoxin receptor 1, CIRL-1, Latrophilin-1, Lectomedin-2, ADGRL1, KIAA0821, LEC2, LPHN1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O94910 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Adhesion G protein-coupled receptor L1 (ADGRL1) is a ~162 kDa protein. Calcium-independent receptor of high affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis. 1. Vitobello, A. et al. (2022) American journal of human genetics 109, 1436-1457. PMID: 35907405 | ||||||||
| Note | For research use only. |
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