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Anti-Human AHI1 Polyclonal Antibody (HV430014)

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Overview
Catalog No.HV430014
Description
Anti-Human AHI1 Polyclonal Antibody (HV430014) is a rabbit polyclonal antibody detecting AHI1. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human AHI1 (Arg596-Ile917).
Target AHI-1, AHI1, Abelson helper integration site 1 protein homolog, Jouberin
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q8N157
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Jouberin (AHI1) is a ~137 kDa protein. Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation. As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development.

1. Lancaster, MA. et al. (2011) Nature medicine 17, 726-31. PMID: 21623382
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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