

| Catalog No. | HW301014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human ALDH3A2 (Met1-Lys428). | ||||||||
| Target | ALDH10, Aldehyde dehydrogenase family 3 member A2, Aldehyde dehydrogenase 10, FALDH, Microsomal aldehyde dehydrogenase, Fatty aldehyde dehydrogenase, ALDH3A2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P51648 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) is a ~54 kDa protein. Catalyzes the oxidation of medium and long chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid. 1. Lloyd, MD. et al. (2007) Journal of enzyme inhibition and medicinal chemistry 22, 584-90. PMID: 18035827 2. Sanders, RJ. et al. (2008) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 22, 2064-71. PMID: 18182499 3. Nakahara, K. et al. (2012) Molecular cell 46, 461-71. PMID: 22633490 4. Keller, MA. et al. (2014) Nature communications 5, 4439. PMID: 25047030 5. Kelson, TL. et al. (1997) Biochimica et biophysica acta 1335, 99-110. PMID: 9133646 6. Verhoeven, NM. et al. (1998) FEBS letters 429, 225-8. PMID: 9662422 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-ALDH3A2 polyclonal antibody at 1μg/ml on various samples.
Lane 1: MCF-7 cell lysate
Lane 2: Hela cell lysate
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