

| Catalog No. | HD673014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human ALX1 Polyclonal Antibody (HD673014) is a rabbit polyclonal antibody detecting ALX1. Suitable for Human, Mouse, and Rat.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human ALX1 (Arg136-Met326). | ||||||||
| Target | ALX homeobox protein 1, ALX1, CART-1, CART1, Cartilage homeoprotein 1 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q15699 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | ALX homeobox protein 1 (ALX1) is a ~36 kDa protein. Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes. Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival. May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1. 1. Gordon, DF. et al. (1996) DNA and cell biology 15, 531-41. PMID: 8756334 2. Cai, RL. (1998) Biochemical and biophysical research communications 250, 305-11. PMID: 9753625 3. Uz, E. et al. (2010) American journal of human genetics 86, 789-96. PMID: 20451171 4. Yuan, H. et al. (2013) Cancer research 73, 1581-90. PMID: 23288509 | ||||||||
| Note | For research use only |
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