

| Catalog No. | HT122014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human ANGPTL7 (Asp126-Pro346). | ||||||||
| Target | Angiopoietin-related protein 7, Angiopoietin-like protein 7, Cornea-derived transcript 6 protein, ANGPTL7, Angiopoietin-like factor, CDT6 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O43827 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Angiopoietin-related protein 7 (ANGPTL7) is a ~40 kDa protein. Has a role in the formation and organization of the extracellular matrix. In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure. Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency. 1. Comes, N. et al. (2011) Genes to cells : devoted to molecular & cellular mechanisms 16, 243-59. PMID: 21199193 2. Toyono, T. et al. (2015) PloS one 10, e0116838. PMID: 25622036 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-Human ANGPTL7 polyclonal antibody at 1ug/mL on recombinant Human ANGPTL7 (Catalog No. HT122012).
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