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Anti-Human AQP3 Recombinant Antibody (SAA2514) (HA985023)

Anti-Human AQP3 Recombinant Antibody (SAA2514)
Anti-Human AQP3 Recombinant Antibody (SAA2514)
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Overview
Catalog No.HA985023
Species reactivityHuman
ApplicationsELISA
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA2514
Clonality Monoclonal
Target AQP-3, AQP3, Aquaglyceroporin-3, Aquaporin-3
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q92482
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Aquaporin-3 (AQP3) is a ~31 kDa protein. Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Also participates in cell permeability to H2O2 and H2O2-mediated signaling. In skin, transports glycerol to the epidermis and stratum corneum, where it maintains hydration, elasticity, and supports lipid biosynthesis for barrier repair. In kidney, contributes to the reabsorption of water, helping the body maintain proper fluid balance.

1. Roudier, N. et al. (2002) The Journal of biological chemistry 277, 45854-9. PMID: 12239222
2. Gotfryd, K. et al. (2018) Nature communications 9, 4749. PMID: 30420639
3. Miller, EW. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 15681-6. PMID: 20724658
Note For research use only
Isotype Control Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)
Images
  • Anti-Human AQP3 Recombinant Antibody (SAA2514)

    SDS-PAGE

    SDS-PAGE for Anti-Human AQP3 Antibody (SAA2514)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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V₁ (Stock Vol.)
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C₂ (Working Conc.)
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