Anti-Human AQP7 Polyclonal Antibody (HT308014)

Name: Anti-Human AQP7 Polyclonal Antibody
Brand: abinScience
SKU: HT308014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HT308014

Description

Anti-Human AQP7 Polyclonal Antibody (HT308014) is a rabbit polyclonal antibody detecting AQP7 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human AQP7 (Phe236-Phe342).

Target

Aquaporin-7, AQP-7, Aquaglyceroporin-7, Aquaporin adipose, AQPap, Aquaporin-7-like, AQP7, AQP7L, AQP9

Purification

Purified by antigen affinity column.

Accession

O14520

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Aquaporin-7 (AQP7) is a ~37 kDa protein. Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Mediates the efflux of glycerol, formed upon triglyceride hydrolysis, to avoid its accumulation in adipocytes and to make it available to other tissues. In the kidney, mediates the reabsorption of glycerol, preventing its loss in urine, again participating to energy homeostasis. In pancreatic beta cells, it also mediates the efflux of glycerol, regulating its intracellular levels.

1. Kondo, H. et al. (2002) European journal of biochemistry 269, 1814-26. PMID: 11952783

2. Gotfryd, K. et al. (2018) Nature communications 9, 4749. PMID: 30420639

3. Mósca, AF. et al. (2018) Cells 7. PMID: 30423801

4. Huang, P. et al. (2023) Nature communications 14, 600. PMID: 36737436

5. Kuriyama, H. et al. (1997) Biochemical and biophysical research communications 241, 53-8. PMID: 9405233

Note

For research use only.

Images

References

Datasheet

Anti-Human AQP7 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human AQP7 Polyclonal Antibody (HT308014)

Overview

Images

References

Datasheet

SDS

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