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Anti-Human ASCL1 Recombinant Antibody (SAA1643) (HW647013)

Anti-Human ASCL1 Recombinant Antibody (SAA1643)
Anti-Human ASCL1 Recombinant Antibody (SAA1643)
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Overview
Catalog No.HW647013
Species reactivityHuman
ApplicationsELISA
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA1643
Clonality Monoclonal
Target hASH1, ASH1, Achaete-scute homolog 1, BHLHA46, ASH-1, ASCL1, Class A basic helix-loop-helix protein 46, HASH1, bHLHa46
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P50553
RRID Anti-Human ASCL1 Antibody (SAA1643) (abinScience Cat# HW647013, RRID:AB_3727404)
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Achaete-scute homolog 1 (ASCL1) is a ~25 kDa protein. Transcription factor that plays a key role in neuronal differentiation: acts as a pioneer transcription factor, accessing closed chromatin to allow other factors to bind and activate neural pathways. Directly binds the E box motif (5'-CANNTG-3') on promoters and promotes transcription of neuronal genes. The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro. Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons.

Note For research use only.
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  • Anti-Human ASCL1 Recombinant Antibody (SAA1643)

    SDS-PAGE

    SDS-PAGE for Anti-Human ASCL1 Antibody (SAA1643)

Formula
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