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Anti-Human ATAT1 Monoclonal Antibody (1A143) (HV487035)

Anti-Human ATAT1 Monoclonal Antibody (1A143)
Anti-Human ATAT1 Monoclonal Antibody (1A143)
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Overview
Catalog No.HV487035
Description
Anti-Human ATAT1 Monoclonal Antibody (1A143) [1A143] (HV487035) is a mouse monoclonal antibody detecting ATAT1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesMouse
ClonalityMonoclonal
IsotypeIgG1
Clone ID1A143
Immunogen E. coli - derived recombinant Human ATAT1 (Met1-Pro196).
Target C6orf134, TAT, MEC17, Alpha-TAT, ATAT1, Alpha-TAT1, Acetyltransferase mec-17 homolog, Alpha-tubulin N-acetyltransferase 1,
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q5SQI0
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Alpha-tubulin N-acetyltransferase 1 (ATAT1) is a ~46 kDa protein. Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.

Note For research use only.
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  • Anti-Human ATAT1 Monoclonal Antibody (1A143)

    SDS-PAGE

    SDS-PAGE for Anti-Human ATAT1 Monoclonal Antibody (1A143)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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