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Anti-Human ATF6B Polyclonal Antibody (HP804014)

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Overview
Catalog No.HP804014
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human ATF6B (Ala2-Arg50).
Target CREBL1, Protein G13, cAMP-responsive element-binding protein-like 1, Activating transcription factor 6 beta, cAMP response element-binding protein-related protein, Cyclic AMP-dependent transcription factor ATF-6 beta, G13, ATF6B, Creb-rp, ATF6-beta, cAMP-dependent transcription factor ATF-6 beta
Purification Purified by antigen affinity column.
Accession Q99941
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Cyclic AMP-dependent transcription factor ATF-6 beta (ATF6B) is a ~76 kDa protein. Precursor of the transcription factor form (Processed cyclic AMP-dependent transcription factor ATF-6 beta), which is embedded in the endoplasmic reticulum membrane. Endoplasmic reticulum stress promotes processing of this form, releasing the transcription factor form that translocates into the nucleus, where it activates transcription of genes involved in the unfolded protein response (UPR).

1. Haze, K. et al. (2001) The Biochemical journal 355, 19-28. PMID: 11256944
Note For research use only.
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Formula
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