

| Catalog No. | HP804014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human ATF6B (Ala2-Arg50). | ||||||||
| Target | CREBL1, Protein G13, cAMP-responsive element-binding protein-like 1, Activating transcription factor 6 beta, cAMP response element-binding protein-related protein, Cyclic AMP-dependent transcription factor ATF-6 beta, G13, ATF6B, Creb-rp, ATF6-beta, cAMP-dependent transcription factor ATF-6 beta | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q99941 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Cyclic AMP-dependent transcription factor ATF-6 beta (ATF6B) is a ~76 kDa protein. Precursor of the transcription factor form (Processed cyclic AMP-dependent transcription factor ATF-6 beta), which is embedded in the endoplasmic reticulum membrane. Endoplasmic reticulum stress promotes processing of this form, releasing the transcription factor form that translocates into the nucleus, where it activates transcription of genes involved in the unfolded protein response (UPR). 1. Haze, K. et al. (2001) The Biochemical journal 355, 19-28. PMID: 11256944 | ||||||||
| Note | For research use only. |
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