

| Catalog No. | HB582014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human ATP8B3 Polyclonal Antibody (HB582014) is a rabbit polyclonal antibody detecting Phospholipid-transporting ATPase IK; 7.6.2.1; ATPase class I type 8B member 3; ATP8B3; ATP1K; FOS37502_2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant human ATP8B3 (Asn503-Leu741). | ||||||||
| Target | Phospholipid-transporting ATPase IK; 7.6.2.1; ATPase class I type 8B member 3; ATP8B3; ATP1K; FOS37502_2 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O60423 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Phospholipid-transporting ATPase IK (ATP8B3) is a ~146 kDa protein. P4-ATPase flippase which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation also seems to be implicated in vesicle formation and in uptake of lipid signaling molecules. May be responsible for the maintenance of asymmetric distribution of phosphatidylserine (PS) in spermatozoa membranes. Involved in acrosome reactions and binding of spermatozoa to zona pellucida. | ||||||||
| Note | For research use only |
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